Levothyroxine treatment is associated with an increased relative risk of overall and organ specific incident cancers - a cohort study of the Swedish population
Read more at https://europepmc.org/article/med/32222650.
Filtyp
Read more at https://europepmc.org/article/med/32222650.
A Bayesian Approach to Validation Substudy Design With Prospective Data Collection Read more at https://journals.lww.com/epidem/Fulltext/2020/07000/Adaptive_Validation….
https://www.lupop.lu.se/article/adaptive-validation-design - 2025-09-13
Atrophy of Ch4 precedes and predicts future dementia in PD and is followed by changes in Ch1/Ch2, reflecting a posterior-anterior pattern of basal forebrain atrophy. Read more at https://doi.org/10.1016/j.nbd.2020.104831.
Read more at https://journals.lww.com/epidem/Fulltext/2020/07000/Reducing_Bias_Due_t….
Read more at https://doi.org/10.1016/j.jad.2020.03.090.
With the rapid development of data science, encompassing big data and artificial intelligence, and with the exponential growth of accessible and highly heterogeneous health-related data, from healthcare providers to user-generated online content, the field of surveillance and health monitoring is changing rapidly. Read more at https://jech.bmj.com/content/74/7/612?rss=1.
https://www.lupop.lu.se/article/glossary-public-health-surveillance-age-data-science - 2025-09-13
Read more at https://link.springer.com/article/10.1007/s10654-020-00659-8.
https://www.lupop.lu.se/article/counterfactual-prediction-not-only-causal-inference - 2025-09-13
In this paper we study approaches for dealing with treatment when developing a clinical prediction model. Analogous to the estimand framework recently proposed by the European Medicines Agency for clinical trials, we propose a ‘predictimand’ framework of different questions that may be of interest when predicting risk in relation to treatment started after baseline. Read more at https://link.sprin
https://www.lupop.lu.se/article/prediction-meets-causal-inference-role-treatment-clinical-prediction-models - 2025-09-13
By enabling adjacent management of less urgent pediatric patients at adequate lower levels of medical care, implementation of a HPCU outside office hours may contribute to fewer and more appropriate pediatric ED visits. Read more at https://journals.sagepub.com/doi/full/10.1177/2150132720926276.
https://www.lupop.lu.se/article/adjacent-primary-care-may-reduce-less-urgent-pediatric-emergency-department-visits - 2025-09-13
The Nordic registers are an extraordinary resource for public health researchers, but continuous quality control and assessment of validity and completeness will be crucial to maintain relevance in a transitioning society. Read more at https://journals.sagepub.com/doi/10.1177/1403494820945919.
This study shows that the pulmonary blood volume variation indexed to the stroke volume is higher in patients with heart failure compared with controls. The mechanisms behind this are lack of systolic suction from the left ventricular atrioventricular plane descent and increased phase shift between the in- and outflow to the pulmonary circulation (~40%), where the phase shift alone accounts for ~3
Participants are invited to submit COST Action proposals contributing to the scientific, technological, economic, cultural or societal knowledge advancement and development of Europe. Multi- and interdisciplinary proposals are encouraged. The Open Call Action proposal submission, evaluation, selection and approval (SESA) procedure is fully science and technology-driven and will ensure a simple, tr
https://www.lupop.lu.se/article/open-call-simple-one-step-application-process - 2025-09-13
Bipolar disorder has long been associated with increased risks for suicidality; though factors associated with dying by suicide remain obscure. Here, we retrospectively examine the associations between the different phases of bipolar illness and other common comorbidities with death by suicide in the 120 days following each discharge for Swedes first admitted as inpatients for bipolar disorder dur
In a longitudinal cohort study based on population-based healthcare data from Skåne, Sweden, we included all persons aged 25–34 years in 1998–2007 (n=149 288) with and without diagnoses of knee injuries according to International Classification of Diseases (ICD)-10. We estimated the HR of future diagnosed knee OA in injured and uninjured persons using Cox regression, adjusted for potential confoun
Compared to the general population, patients with alcohol and drug addiction have an increased risk of additional hazardous lifestyles and suffer from more chronic diseases, adding to their already significantly higher morbidity and mortality. The objective of this study was to test the efficacy of the Very Integrated Program (VIP) on treatment and health outcomes for patients diagnosed with alcoh
QoL assessment using the SF-36 (36-item short form health survey) questionnaire. Patients with post-cholecystectomy BDI needing hepaticojejunostomy (HJ) were compared to all other treatments (BDI repair) and to patients without BDI at cholecystectomy (controls). Read more athttps://www.tandfonline.com/doi/full/10.1080/00365521.2020.1800076
Study population included all adults aged 50 years and older in Sweden (n = 2775736). PD was defined as having at least one registered diagnosis of PD in the National Patient Register. The incidence of PD in different first-generation immigrant groups versus Swedish-born individuals was assessed by Cox regression, expressed as hazard ratios (HRs) and 95% confidence intervals (CI). The models were
Air pollution is estimated to cause more than 7000 deaths annually in Sweden alone. To reduce the impact of air pollution and to plan and build sustainable cities, it is vital that research is translated into efficient decisions and practice. However, how do civil servants in a municipality access research results? How do they normally find relevant information, and what obstacles are there to acc
A cross-sectional sample of 68 participants (mean age 66) with UE impairments were followed up at 12 months post stroke. Stroke severity at onset was moderate for the majority. Manual ability was assessed by the patient-reported outcome measure ABILHAND Questionnaire. Read more athttps://www.tandfonline.com/doi/full/10.1080/09638288.2018.1557265
Save the date: Meeting on GDPR and how it will affect people doing research. Update: More information available at https://www.lupop.lu.se/event/forskning-och-den-nya-dataskyddsforordningen Den 5 april kl. 13-16 bjuder vi in till en träff för att diskutera vad GDPR innebär för forskningen och för dig som forskar.Representanter för Region Skåne och för Lunds universitet kommer och reder ut begreppe
https://www.lupop.lu.se/article/how-will-gdpr-affect-me - 2025-09-13